Is there a drop-in replacement for R-410A?

Author: Dr. Kianna Hagenes  |  Last update: Sunday, December 21, 2025

ComStar's RS-53 (R470A) is the world's only drop-in retrofit replacement for existing R410a systems. At 909, RS-53 has a GWP that is effectively 56% lower than R410a. Additionally, RS-51 (R470B) has a GWP of 717 which is 80% lower than R404a, R507 and half of R448A and R449A.

What is the drop-in replacement for 410A?

RS-53 (R470A) has been specifically designed to mitigate these changes to the refrigerant user by reducing the direct GWP of the refrigerant while not compromising its energy efficiency and technical properties as a suitable Drop-in replacement for R410A.

What can I replace 410A refrigerant with?

The replacements for R-410A are the two A2Ls, Forane® R-32 and R-454B.

Is R-454B a drop-in replacement for R-410A?

No. R-454B is NOT a drop-in replacement for R-410A.

Is R-32 a drop-in replacement for R-410A?

R32 is not suitable as a drop-in replacement for R410A and must only be used in systems specifically designed for R32.

The FIRST 410A Drop-In Refrigerant HITS the Market!

What happens if you put R32 in a R410 system?

R32 has a higher compressor discharge temperature than R410A, and will increase wear on the compressor, reducing its life significantly. Should any problem arise from a system change such as this, any liability would rest ENTIRELY with the person who carried out the change.

Can you replace 410A with R-22?

R-22 uses simple mineral oil, non-toxic, safe, stable, etc. while R-410a uses a somewhat exotic Poly o Ester (POE) oil typically found in jet turbine engines. The refrigerant used MUST match the oil present in the system, which is one reason why you can't replace the R-22 with R410a in a system.

Will R-410A be phased out?

The impending phaseout of R-410A, a widely used refrigerant in HVAC systems, marks a huge shift for homeowners and the HVAC industry. Set to take effect on December 31, 2024, this change is driven by global efforts to reduce greenhouse gas emissions and comply with environmental regulations.

Which is better R-32 or R-454B?

Comprehensive Environmental Impact Metrics

This means systems using R32 typically consume less energy over their lifetime, resulting in fewer indirect emissions. R454B, while also efficient, may require a larger charge size to achieve similar cooling performance, which can increase its overall environmental footprint.

Can you reuse R-22 line set for R-410A?

So what the manufacturer recommends, the best option, is if you're going to go from an R22 unit to an R410 unit, that you should have your line set replaced at the same time. So everything is new. There's no contamination, there's no possibility of contamination.

What will replace 410A in 2025?

Cooling systems shifting from R-410a to newer refrigerants like R-454B refrigerant and R-32 refrigerant will be implemented in 2025. These new coolants are engineered to be friendlier to the environment and meet updated regulations about global warming.

What refrigerant can be mixed with R-410A?

A small amount of R 22 left in a 410A system will not sludge the oil. This is because most POE oils are mixable (meaning they mix well) with any refrigerant even R 22.

Can R-454B be retrofitted into existing R-410A or R-22 systems?

ACHR NEWS: As a mildly flammable refrigerant, R-454B can't be retrofitted into existing R-22 and R-410A systems.

What is the best replacement for R-410A?

What are the best alternatives to R410A in air conditioning and commercial heat pumps? R32, R452B, and R454B are all good options for air conditioning systems. However, the best option varies by application. Refrigerants with ultra-low GWP will be important in the longer term.

Which can be considered as a drop-in replacement refrigerant?

Examples of Drop-In Refrigerants:

R437A and R438A: Replacements for R22 in refrigeration and air-conditioning systems. R449A or R448A: Alternatives to R404A, with significantly lower GWP. R513A: A replacement for R134a with low global warming potential (GWP)

Why is 410A so expensive right now?

Regulatory Changes: As the phase-out continues to restrict production levels and importation, the R-410A price will likely increase. Manufacturing Costs: Fluctuations in the cost of raw materials and manufacturing can also influence the price of refrigerants.

What is the new refrigerant in 2024?

Basically, federal standards will require a new type of refrigerant to be used in brand-new home HVAC systems. Right now, cooling systems are required to use HFC and HCFC refrigerants, like R410a. The new guidelines will require A2L refrigerant to be used instead for all systems manufactured after a certain time.

Is R32 refrigerant legal in the US?

Regulatory - There are no published regulations or granted EPA petitions that state R-32 will be prohibited in the U.S. after 2029. In fact, R-32 is a single component refrigerant, while R-454B is a blend that consists of nearly 70% R-32.

Is r448 a drop in for R22?

R448A is not a “Drop-in” Replacement

The retrofit procedures listed here have been developed by Honeywell to address these issues and to help technicians perform successful retrofits of R22 systems utilizing positive- displacement (reciprocating, rotary, scroll or screw) compressors.

Will there be a drop in replacement for R-410A?

ComStar's RS-53 (R470A) is the world's only drop-in retrofit replacement for existing R410a systems. At 909, RS-53 has a GWP that is effectively 56% lower than R410a. Additionally, RS-51 (R470B) has a GWP of 717 which is 80% lower than R404a, R507 and half of R448A and R449A.

What refrigerant will Trane use in 2025?

R-454B. R-454B is the newest refrigerant, which will gradually replace R-410A, the refrigerant used in HVAC manufacturing from 2010 until the phase-out is complete in January 2025.

What is the lifespan of R-410A refrigerant?

The lifespan of R410A refrigerant is typically 10-15 years, depending on its usage and maintenance. Proper installation and maintenance can extend the life of the refrigerant significantly, while improper use or lack of maintenance can significantly decrease its lifespan.

What is 410A being replaced with?

R410-a will be replaced by A2L refrigerants, which are a class of refrigerants that have higher efficiency and lower GWP (Global Warming Potential). The two foremost R410a replacements are R-32 and R-454B. R-32: Zero ozone depletion.

How much does it cost to convert R-22 to R-410A?

How much will an R-22 to R-410A conversion cost? The actual cost will depend on many things, including where you live, but most of the time R-22 conversions start at around $2,000 and go up from there. The higher end of that range is somewhere around $4,500 to $4,600.

What happens if you accidentally put 410A in a R-22 system?

Since R410A refrigerant is charged under higher pressure, charging an R22 system with it will increase the force within the coolant lines. The pressure can become high enough for parts of the system to rupture. At the very least, leaks will occur. Mixing refrigerants is not an option either.

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