Toxicity category I is highly toxic and severely irritating, Toxicity category II is moderately toxic and moderately irritating, Toxicity category III is slightly toxic and slightly irritating, Toxicity category IV is practically non-toxic and not an irritant.
Toxicity ratings are expressed in parts per million of chemical exposure. Like bowling, a high score is better and safer. It means you can be exposed to more of the chemical without any adverse effect.
Equivalent toxicity score (ETS) is defined as a quantitative measurement of the overall toxicity severity for each patient. The mapping between adjusted grade and original toxicity in Section 2.1 is flexible because the estimated ETS of each patient will be further normalized to a range from 0 to 1 in Section 2.3.
In general, the convention 1 — mild, 2 - moderate, 3 = severe and 4 - life-threatening is aimed for.
A substance is considered extremely toxic if it has an LD50 of less than 5 mgs/kg of animal body weight. To humans, this is the equivalent of a taste (less than 7 drops). It is Highly toxic if it has an LD50 of between 5 and 50 mg/kg of animal body weight to a human, this would be about a teaspoon.
Toxicity Score
A site's toxicity is scored using a 0–100 scale with 0 being clean and 100 being extremely toxic. The more toxic links piled up in a site's backlink profile, the higher its toxicity score.
The FDA is a standardized test which relies on a 9-point rating scale applied to a patient. It provides information based on the observation of oral structures, functions and speech. The test evaluates the following functions: reflexes, respiration, tongue, lips, the soft palate, larynx, intelligibility.
One such population-level measure is the median lethal dose, LD50 (lethal dose, 50%). This is defined as the dose required to kill half the members of a specific animal population when entering the animal's body by a particular route. LD50 is a general indicator of a substance's toxicity within a short space of time.
Normal: No unexpected drugs are found in the sample. Levels of prescription or non-prescription medicines found in the sample are within the effective (therapeutic) range.
Toxicity category I is highly toxic and severely irritating, Toxicity category II is moderately toxic and moderately irritating, Toxicity category III is slightly toxic and slightly irritating, Toxicity category IV is practically non-toxic and not an irritant.
Severe (Grade 3) Potentially Life
Threatening.
Class I: very toxic. Class II: toxic. Class III: harmful. Class IV : corrosive.
Toxicity weights are based upon the single most sensitive adverse effect for the given exposure route and do not consider differences in the type, number, and severity of effects. For example, liver toxicity is weighted in the same way that neurotoxicity is weighted.
Health, Fire, and Reactivity receive a numeric rating from 0 to 4 based on the severity of hazard in that category, with 0 being non-hazardous and 4 being the most severe. Specific hazards include Oxidizer, Corrosive, Water Reactive, etc.
The Likert scale is an extremely useful rating scale to measure customer opinions. For example, a company may use the Likert scale to determine the effectiveness of its customer support team. They offer respondents the opportunity to respond from “Extremely responsive” to “Not responsive at all.”
FDA Approval: What it means. FDA approval of a drug means that data on the drug's effects have been reviewed by CDER, and the drug is determined to provide benefits that outweigh its known and potential risks for the intended population.
For convenience, we see organizations using the same rating scale for all content and areas in an employee's evaluation - from goals to competencies. This is more often than not a 5 point rating scale (5– Outstanding, 4– Exceeds Expectations, 3- Meets Expectations, 2- Needs Improvement, 1- Unacceptable).
LC50 is defined as the concentration in air at which 50 percent of the test animals (rats or mice) died, usually within 1 hour. A substance is considered extremely toxic if it has an LD50 of less than 5 mgs/kg of animal body weight. To humans, this is the equivalent of a taste (less than 7 drops).
Drug toxicity can occur if a drug's concentration exceeds a therapeutic range. This may occur secondary to an unintentional or intentional overdose, or because of drug accumulation. Toxicity is the state of being noxious, or is described as a drug's ability to poison the body.
Toxicity criteria are chemical-specific numerical values that reflect the potency of a chemical or contaminant (5).
Types. There are generally five types of toxicities: chemical, biological, physical, radioactive and behavioural.
The basic tool for determining toxicity of substances to marine and aquatic organisms is the toxicity test. In its simplest form, toxicity testing is taking healthy organisms from a container of clean water and placing into one containing the same water with a known concentration of a pollutant.
There are various branches of toxicology i.e. analytical toxicology, clinical toxicology, forensic toxicology, veterinary toxicology, aquatic toxicology, environmental toxicology, etc.