What are three types of microbes that are extremely resistant to antimicrobial treatment?

Author: Prof. Janice Bergnaum PhD  |  Last update: Wednesday, January 28, 2026

Arguably the most widely known drug-resistant infections is methicillin-resistant Staphylococcus aureus or MRSA. This resistant infection is often associated with hospitals. Others you may have heard of include C. diff (clostridium difficile), drug-resistant malaria and streptococcus pneumoniae.

What are 3 examples of antibiotic-resistant bacteria?

Important examples of antimicrobial resistance strains of bacteria are:
  • methicillin-resistant Staphylococcus aureus (MRSA)
  • vancomycin-resistant Enterococcus (VRE)
  • multi-drug-resistant Mycobacterium tuberculosis (MDR-TB)
  • carbapenemase-producing Enterobacterales (CPE).

What are the three most resistant groups of microbes?

The bacterial strains staphylococci, enterococci, and pneumococci pose some of the most serious problems in terms of antimicrobial resistance. Scientists have now acquired detailed information about how these bacteria develop drug resistance.

What are the three types of antimicrobial resistance?

Examples of antimicrobial resistance include:
  • Antibiotic-resistant bacteria, like MRSA, carbapenem-resistant enterobacterales (CREs) and Pseudomonas aeruginosa.
  • Antifungal-resistant fungi, like Candida auris and Aspergillus fumigatus.
  • Antiviral-resistant versions of certain viruses, like HIV, influenza, and hepatitis C.

What are 3 ways microbes become resistant to antimicrobial drugs?

However, over time, bacteria can defeat antibiotics in the following ways:
  • Survival of the Fittest (Natural Selection) ...
  • Biological Mutations. ...
  • DNA Exchange. ...
  • Rapid Reproduction. ...
  • Antibiotic-Resistant Bacteria and Effectiveness of Those Drugs. ...
  • Staph Aureus. ...
  • Campylobacter Infections. ...
  • Next Steps.

Mechanisms of antibiotic resistance

What are the 3 types of antimicrobials?

There are three types of public health antimicrobials: sterilizers, disinfectants, and sanitizers.

What are the two most resistant microbes to antimicrobial agents?

The high priority category includes bacteria such as Enterococcus faecium and Staphylococcus aureus that are resistant to various antibiotics, such as vancomycin and fluoroquinolones.

What is the most common type of antimicrobial resistance?

MRSA is one of the most common antibiotic-resistant bacteria. Symptoms of MRSA infection often begin as small red bumps on the skin that can progress to deep, painful abscesses or boils, which are pus-filled masses under the skin. These need to be surgically opened and drained.

What are the 4 classifications of antimicrobial drugs?

Antibacterials act against bacteria, antivirals act against viruses, antifungals act against fungi, and antiprotozoals act against protozoa (www.amrls.cvm.msu.edu).

What are the most resistant microbes?

Arguably the most widely known drug-resistant infections is methicillin-resistant Staphylococcus aureus or MRSA. This resistant infection is often associated with hospitals. Others you may have heard of include C. diff (clostridium difficile), drug-resistant malaria and streptococcus pneumoniae.

What are the three groups of microbes?

The most common types are bacteria, viruses and fungi. There are also microbes called protozoa.

Which of the following microbes is the most resistant to killing?

Endospores are considered the most resistant structure of microbes. They are resistant to most agents that would normally kill the vegetative cells they formed from. Mycobacterial infections are notoriously difficult to treat.

What is a bacteria resistant to antibiotics treatment?

How do healthcare providers treat antibiotic-resistant bacteria? Treatment options are often limited. Providers look for a type of antibiotic, or a combination of medicines, that'll treat your infection. For example, carbapenems are antibiotics that work well against antibiotic-resistant bacteria.

What types of microorganisms would be killed by antibiotic treatment?

Various microorganisms have medical significance, including bacteria, viruses, fungi, and parasites. Antibiotics are compounds that target bacteria and, thus, are intended to treat and prevent bacterial infections.

What are the 3 threat levels of antibiotic resistant bacteria?

The germs are listed in three categories—urgent, serious and concerning—based on level of concern to human health.

What antibiotic kills all infections?

There is no one type of antibiotic that cures every infection. Antibiotics specifically treat infections caused by bacteria, such as Staph., Strep., or E. coli., and either kill the bacteria (bactericidal) or keep it from reproducing and growing (bacteriostatic).

What is the strongest antimicrobial?

The carbapenems, imipenem and meropenem, are considered the most potent of any antibiotic class, and are for use in serious infections or when resistance compromises all other agents.

What are the classification of antimicrobial resistance?

Antimicrobial resistance mechanisms fall into four main categories: (1) limiting uptake of a drug; (2) modifying a drug target; (3) inactivating a drug; (4) active drug efflux.

What are antimicrobial-resistant organisms?

Antimicrobial resistance (AR) happens when germs develop the ability to defeat the drugs designed to kill them. AR has the potential to affect people at any stage of life, as well as the healthcare, veterinary and agriculture industries. This makes it one of the world's most urgent public health problems.

What is the strongest antibiotic resistant bacteria?

The Top 10 antibiotic-resistant bacteria include:
  • Clostridioides difficile (C. ...
  • Carbapenem-resistant Enterobacteriaceae (CRE)
  • Multi-drug resistant Mycobacterium tuberculosis (MDR-TB)
  • Carbapenam-resistant Acinetobacter.
  • Drug-resistant Neisseria gonorrhoeae.
  • Drug-resistant Candida auris (C.

What organism is most resistant to antimicrobial agents?

Leading antimicrobial drug-resistant diseases
  • Mycobacterium tuberculosis. The bacterium that causes tuberculosis (TB) ...
  • C. difficile. ...
  • VRE. (Vancomycin-resistant Enterococci) ...
  • MRSA. (Methicillin-resistant Staphylococcus aureus) ...
  • Neisseria gonorrhoea. The bacterium that causes gonorrhea. ...
  • CRE.

What are 3 microbial forms that are most resistant to chemical disinfectants?

Fungal spores and non-enveloped viruses are generally less susceptible. Mycobacteria, bacterial endospores, and protozoal oocysts are highly resistant to most disinfectants.

What is the hardest bacterial infection to get rid of?

Strains of pathogens that've developed resistance to multiple drugs are the hardest to get rid of. Infections like MRSA and CREs are often resistant to more than one type of antibiotic, so finding one that's effective (or a combination of medications that work together) can be challenging and take a long time.

What is the strongest natural antibiotic for humans?

Seven best natural antibiotics
  1. Garlic. Cultures across the world have long recognized garlic for its preventive and curative powers. ...
  2. Honey. Since ancient times, people have used honey due to its wound-healing activity and antimicrobial properties. ...
  3. Ginger. ...
  4. Echinacea. ...
  5. Goldenseal. ...
  6. Clove. ...
  7. Oregano.

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