How carcinogenic is DEET?

Author: Zakary Spencer  |  Last update: Monday, December 15, 2025

Researchers have not found any evidence that DEET causes cancer in animals or humans. DEET has been classified by the United States Environmental Protection Agency (U.S. EPA) as "not classifiable as a human carcinogen", which means that there is not enough evidence to say that it does or does not cause cancer.

Does DEET cause cancer in humans?

The U.S. Department of Health and Human Services (DHHS) has not classified DEET as to its carcinogenicty (cancer causing ability). The U.S. Environmental Protection Agency (EPA) has determined that DEET in not classifiable as a human carcinogen.

Why is DEET banned in Europe?

DEET is a widely used repellent that deters pests by making it harder for them to smell humans. Despite being effective, it has faced controversy over potential health and environmental impacts, including skin irritation and toxicity concerns. Some countries have even banned DEET due to these risks.

How harmful is DEET?

This study tests the effects of DEET exposure on human health using population-based data. The results indicate that DEET exposure may not be associated with increased risk for negative health outcomes. The implications suggest that DEET exposure is safe for human use.

Can DEET be absorbed through skin?

It is absorbed through the skin and digestive tract, so it is likely that DEET can also be absorbed through the lungs and into the blood. DEET in the lungs can be coughed up and swallowed, if it is not absorbed first.

Ask Dr. Nandi: How safe is Deet?

What happens if you don't wash off DEET?

Very often, people don't wash the product off their skin after returning indoors. This can result in overexposure, especially in cases where a product is applied too often (at short intervals) or daily for several days. A small amount of DEET is absorbed into the body when applied to the skin.

Is DEET a neurotoxin?

DEET is a documented neurotoxin, meaning it can negatively impact the nervous system. When mixed with permethrin, another pesticide, animal studies show the mixture can cause the death of neurons in the brain and disease in the offspring of exposed adults.

Is it bad to wear DEET everyday?

According to the Centers for Disease Control and Prevention (CDC) , DEET products are usually safe as long as people follow their label instructions and do not use them heavily. When choosing a DEET product, a person must use the lowest percentage necessary for the amount of time they will be outside.

Is DEET banned in Canada?

Health Canada decided to limit DEET concentration to 30% in the country since 2002 due to an increased long-term risk observed with repeated applications. DEET is often sold and used in spray or lotion in concentrations up to 100%.

Is 80% DEET too much?

Both products are considered safe and effective when used in accordance with the instructions on the labels. DEET is available in concentrations from 10 to 80 per cent. Concentrations of more than 30 per cent may be dangerous and should be avoided.

What is the controversy with DEET?

There is no reliable evidence that deet causes cancer.

A Swedish study did find that men who used insect repellent for 115 days or longer faced an increased risk of developing testicular cancer.

Which is worse for you, picaridin or DEET?

Studies have shown that Picaridin is effective, safe and has fewer unpleasant qualities than DEET. Picaridin is odorless, does not melt plastics, or feel oily on skin.

Is DEET banned in Switzerland?

Most insect repellents contain DEET (diethyltoluamide) or icaridin. Products which provide protection for up to four hours are approved by the Swiss Tropical and Public Health Institute.

Why does DEET have a bad reputation?

Why does DEET have a reputation for being harmful? DEET is neither intended nor safe for ingestion. Dr. Amin notes that oral intake can result in side effects such as nausea, vomiting, and (in rare cases) seizures.

Does DEET cause liver damage?

N, N-diethyl-meta-toluamide (DEET) is a repellent used since the 1950s and is metabolized by the liver and excreted in urine. DEET toxidrome ranges from GI upset to neurologic toxicity. However, liver injury is not a commonly attributed phenomenon.

Is picaridin a carcinogen?

Picaridin has been classified as not likely to be a human carcinogen. Because of Picaridin's unusual use pattern (direct application to human skin), the Agency believes it is prudent to require clear, common sense use directions and restrictions on Picaridin product labels.

Why avoid DEET?

Very rarely, exposure to DEET has been associated with seizures in people. Most of these reactions have happened after drinking products with DEET in them or using the products in ways that do not follow label directions. Reports of pets being exposed to DEET in amounts that would make them sick are rare.

What is a good alternative to DEET?

For more than 60 years, DEET has reigned as the undisputed champion of insect repellents. No longer. There's now a potentially better alternative on the market: picaridin. Both DEET and picaridin are proven to be effective at fending off ticks—and are superior to other repellents when it comes to protection time.

Is 100% DEET unsafe?

Dr. Bloomquist said that DEET-containing products are safe as long as they're applied correctly — meaning only to exposed skin and not sprayed directly onto the face or broken skin.

Is DEET harmful to the human body?

Occasionally, there have been reports of people having negative reactions after excessive use of repellents containing DEET. These effects included seizures, uncoordinated movements, agitation, aggressive behavior, low blood pressure, and skin irritation.

Is DEET legal in Europe?

Yes, our Expedition 100+ DEET Insect Repellent spray remains compliant and available for sale in the UK and Ireland.

What is the safest bug spray to use?

DEET, picaridin, and natural oils like lemon and eucalyptus oil are all very common and safe ingredients found in bug repellent. Some people prefer to stay away from DEET, as it can burn when it gets in your eyes and often comes with a potent smell.

Is DEET a carcinogen?

DEET has been classified as a Group D carcinogen (not classifiable as a human carcinogen.) Although DEET's use has been implicated in seizures among children, the Agency believes that the incident data are insufficient to establish DEET as the cause of the reported effects.

Why did they ban DEET?

Kim said a 1991 review found many cases where high DEET concentrations were linked to severe skin reactions and neurological problems including seizures. Doctors also onsidered DEET to be the probable cause of the deaths of three children, although the link was not proven, she said.

Is DEET absorbed through skin?

DEET concentrations higher than 30% are not more effective and the chemical (which is absorbed through the skin) in high amounts can be toxic. Follow the directions on the label.

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